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Candidemia Treatment
What is candidemia?
Before one embarks upon the knowledge of the possible treatment of candidemia, it is important to know what candidemia is all about. It is basically Candida in isolation from blood samples.
Although initially medical researchers did not take candidemia very seriously, research in this field reached new heights when it was found out that it could not be ignored because of its association with mortality and morbidity. In non cancer patients, candidemia is associated with twenty six to seventy five percent mortality and in cancer patients the range is thirty percent to seventy two percent.
How can you fight candidemia?
For candidemia treatment, there are two basic parts. First and foremost, attention should be devoted to the source of the fungemia. In order to treat this, one needs to identify the fungemia and then study it. The treatment varies from person to person depending on the constituency of the individual’s body. For patients who are not neutropenic, it has been seen that in most cases, the source of the fungemia is an intravascular catheter. In case of such a possibility, the removal of the catheter is the best way to deal with the fungemia.
Other very common sources of fungemia are urinary tract infections and localized infections. In case of local infections, you need to ensure that they are treated immediately. If you are suffering from a urinary tract infection, you need to go ahead and visit a doctor and get the infection treated immediately.
The second phase of the treatment revolves around the application of an antifungal agent. This is a very important part of the candidemia treatment. There are numerous antifungal agents and you can go for one that your doctor advises to you. However, out of the ones available in the market, amphocetrin B and fluconazole are the ones which are most easily available.
In fact, the two antifungals mentioned above are most commonly used for candidemia treatment. They are also very effective for treatment in patients who are chronically suffering from the disease or are critical.
Medical researchers are currently working on a new kind of candidemia treatment which involves an intravenous concoction of itraconazole. The study is currently going on and if things work out fine, we might soon have a great therapy for candidemia which works wonders. However, right now there is no further information available on this because it is still under development.
Dose of the antifungal agents
Another thing which is of primary importance in candidemia treatment is the dose of the antifungal agent. Although the doses depend according to the health of the patient and his body constitution, it is good to have a basic idea of what kind of dose you should administer for candidemia treatment. For stable patients with no other major problems, 400 mg of Fluconazole is a good bet. For those having amphotericin B as the antifungal agents, 0.5 mg/kg/ day is the standard dosage. In case the patient is not stable, the fluconazole should be given intravenously.
Thus, while going for candidemia treatment, it is best to keep the above things in mind.
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